How a Result Sdy Tool Can Help You Achieve Your Organization GoalsHow a Result Sdy Tool Can Help You Achieve Your Organization Goals
The sdy gene has been shown to be an important regulator of sperm maturation in trout (O. trutta). However, little is known about how the sdy gene influences testicular differentiation in other fish. To begin to address this question, we have performed a genome-wide association study of the sdy gene in salmonid species. We have found that sdy shares a low degree of identity with the C-terminal domain of interferon regulatory factor 9 (Irf9) proteins, but certain stretches of highly conserved amino acids are present in both proteins. In addition, we have also compared the sdy sequence with several fish Irf9 sequences to identify genes that are co-localized with sdy in sex-specific patterns in salmonids.
This suggests that sdy may regulate testicular development in fish by acting as a dosage factor, similar to how the dmrt1 gene affects sex determination in chickens. Our results further suggest that sdy is an important regulator of sex determination in other fish.
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